35 games, 2 exhibitions
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/18/1989 | H | Venezuela (Exhibition) | 12 | W | 102 | 74 | 18,984 | Louisville | Ky. | Freedom Hall | |||||
| 11/24/1989 | N | Chaminade | 12 | W | 89 | 70 | 1-0 | 0-0 | 3,000 | Lahaina | Hawaii | Lahaina Civic Center | 1989 Maui Invitational | ||
| 11/25/1989 | N | 11 | Missouri | 12 | L | 79 | 82 | 1-1 | 0-0 | 3,000 | Lahaina | Hawaii | Lahaina Civic Center | 1989 Maui Invitational | |
| 11/26/1989 | N | Villanova | 12 | W | 83 | 69 | 2-1 | 0-0 | 3,000 | Lahaina | Hawaii | Lahaina Civic Center | 1989 Maui Invitational | ||
| 12/02/1989 | N | 19 | Notre Dame | 13 | W | 84 | 73 | 3-1 | 0-0 | 40,128 | Indianapolis | Ind. | Hoosier Dome | 1989 Big Four Classic | |
| 12/04/1989 | H | Cleveland State | 11 | W | 104 | 77 | 4-1 | 0-0 | 18,968 | Louisville | Ky. | Freedom Hall | |||
| 12/06/1989 | H | Vanderbilt | 11 | W | 101 | 75 | 5-1 | 0-0 | 19,375 | Louisville | Ky. | Freedom Hall | |||
| 12/09/1989 | H | Western Kentucky | 11 | W | 75 | 61 | 6-1 | 0-0 | 19,407 | Louisville | Ky. | Freedom Hall | |||
| 12/11/1989 | H | Athletes in Action (Exhibition) | 10 | W | 93 | 89 | 18,958 | Louisville | Ky. | Freedom Hall | |||||
| 12/16/1989 | H | New Mexico | 10 | W | 78 | 49 | 7-1 | 0-0 | 19,360 | Louisville | Ky. | Freedom Hall | |||
| 12/18/1989 | H | Austin Peay | 9 | W | 93 | 59 | 8-1 | 0-0 | 19,114 | Louisville | Ky. | Freedom Hall | |||
| 12/30/1989 | A | Kentucky | 8 | W | 86 | 79 | 9-1 | 0-0 | 24,089 | Lexington | Ky. | Rupp Arena | |||
| 01/04/1990 | H | Cincinnati | 8 | L | 66 | 71 | 9-2 | 0-1 | 19,265 | Louisville | Ky. | Freedom Hall | |||
| 01/07/1990 | H | 15 | UCLA | 8 | W | 97 | 80 | 10-2 | 0-1 | 19,455 | Louisville | Ky. | Freedom Hall | ||
| 01/11/1990 | A | South Carolina | 11 | W | 79 | 66 | 11-2 | 1-1 | 11,244 | Columbia | S.C. | Carolina Coliseum | |||
| 01/14/1990 | A | Florida State | 11 | W | 73 | 66 | 12-2 | 2-1 | 11,093 | Tallahassee | Fla. | Tallahassee-Leon County Civic Center | |||
| 01/18/1990 | A | Tulane | 10 | W | 109 | 96 | 13-2 | 3-1 | 3,687 | New Orleans | La. | Fogelman Arena | |||
| 01/20/1990 | H | Memphis | 10 | W | 86 | 69 | 14-2 | 4-1 | 19,491 | Louisville | Ky. | Freedom Hall | |||
| 01/27/1990 | A | DePaul | 4 | L | 62 | 66 | 14-3 | 4-1 | 16,602 | Rosemont | Ill. | Rosemont Horizon | |||
| 01/29/1990 | H | Southern Mississippi | 10 | W | 105 | 88 | 15-3 | 5-1 | 19,236 | Louisville | Ky. | Freedom Hall | |||
| 02/01/1990 | H | Virginia Tech | 10 | W | 96 | 69 | 16-3 | 6-1 | 19,308 | Louisville | Ky. | Freedom Hall | |||
| 02/04/1990 | A | Ohio State | 10 | L | 88 | 91 | OT | 16-4 | 6-1 | 13,276 | Columbus | Ohio | St. John Arena | ||
| 02/06/1990 | H | Florida State | 15 | W | 69 | 50 | 17-4 | 7-1 | 19,355 | Louisville | Ky. | Freedom Hall | |||
| 02/08/1990 | H | South Carolina | 15 | W | 95 | 77 | 18-4 | 8-1 | 19,385 | Louisville | Ky. | Freedom Hall | |||
| 02/10/1990 | H | 16 | Georgia Tech | 15 | L | 84 | 94 | 18-5 | 8-1 | 19,559 | Louisville | Ky. | Freedom Hall | ||
| 02/15/1990 | A | Virginia Tech | 18 | W | 97 | 78 | 19-5 | 9-1 | 9,473 | Blacksburg | Va. | Cassell Coliseum | |||
| 02/17/1990 | A | Virginia | 18 | W | 72 | 56 | 20-5 | 9-1 | 8,864 | Charlottesville | Va. | University Hall | |||
| 02/20/1990 | A | Memphis | 16 | L | 68 | 82 | 20-6 | 9-2 | 11,200 | Memphis | Tenn. | Mid-South Coliseum | |||
| 02/24/1990 | A | 4 | Nevada-Las Vegas | 16 | L | 81 | 91 | 20-7 | 9-2 | 19,099 | Las Vegas | Nev. | Thomas & Mack Center | ||
| 02/27/1990 | H | Tulane | 21 | W | 99 | 85 | 21-7 | 10-2 | 19,587 | Louisville | Ky. | Freedom Hall | |||
| 03/01/1990 | A | Cincinnati | 21 | W | 86 | 71 | 22-7 | 11-2 | 13,176 | Cincinnati | Ohio | Shoemaker Center | |||
| 03/03/1990 | A | Southern Mississippi | 21 | W | 73 | 71 | 23-7 | 12-2 | 8,095 | Hattiesburg | Miss. | Reed Green Coliseum | |||
| 03/08/1990 | N | Tulane | 18 | W | 79 | 66 | 24-7 | 12-2 | 10,257 | Biloxi | Miss. | Mississippi Coast Coliseum | 1990 Metro Tournament Quarterfinal | ||
| 03/09/1990 | N | Memphis | 18 | W | 76 | 73 | 25-7 | 12-2 | 10,257 | Biloxi | Miss. | Mississippi Coast Coliseum | 1990 Metro Tournament Semifinal | ||
| 03/10/1990 | N | Southern Mississippi | 18 | W | 83 | 80 | 26-7 | 12-2 | 10,257 | Biloxi | Miss. | Mississippi Coast Coliseum | 1990 Metro Tournament Final | ||
| 03/15/1990 | N | Idaho | 16 | W | 78 | 59 | 27-7 | 12-2 | 10,298 | Salt Lake City | Utah | Huntsman Center | 1990 NCAA Tournament West Regional First Round | ||
| 03/17/1990 | N | Ball State | 16 | L | 60 | 62 | 27-8 | 12-2 | 13,025 | Salt Lake City | Utah | Huntsman Center | 1990 NCAA Tournament West Regional Second Round |