30 games, 1 exhibition
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/22/1998 | H | Western Kentucky | W | 99 | 78 | 1-0 | 0-0 | 19,132 | Louisville | Ky. | Freedom Hall | ||||
| 12/05/1998 | A | Mississippi | L | 69 | 88 | 1-1 | 0-0 | 5,572 | Oxford | Miss. | Tad Smith Coliseum | ||||
| 12/07/1998 | H | Towson | W | 106 | 73 | 2-1 | 0-0 | 17,821 | Louisville | Ky. | Freedom Hall | ||||
| 12/12/1998 | H | Athletes in Action (Exhibition) | W | 91 | 71 | 14,823 | Louisville | Ky. | Freedom Hall | ||||||
| 12/17/1998 | A | 7 | North Carolina | L | 72 | 77 | 2-2 | 0-0 | 17,458 | Chapel Hill | N.C. | Dean E. Smith Center | |||
| 12/19/1998 | H | DePaul | W | 90 | 63 | 3-2 | 1-0 | 18,128 | Louisville | Ky. | Freedom Hall | ||||
| 12/21/1998 | A | Dayton | W | 68 | 65 | 4-2 | 1-0 | 12,774 | Dayton | Ohio | University of Dayton Arena | ||||
| 12/26/1998 | H | 3 | Kentucky | W | 83 | 74 | 5-2 | 1-0 | 20,051 | Louisville | Ky. | Freedom Hall | |||
| 12/30/1998 | H | Morgan State | W | 95 | 47 | 6-2 | 1-0 | 18,219 | Louisville | Ky. | Freedom Hall | ||||
| 01/02/1999 | A | 13 | Michigan State | L | 57 | 69 | 6-3 | 1-0 | 14,659 | East Lansing | Mich. | Breslin Center | |||
| 01/06/1999 | H | Saint Louis | W | 93 | 70 | 7-3 | 2-0 | 18,816 | Louisville | Ky. | Freedom Hall | ||||
| 01/10/1999 | A | South Florida | W | 95 | 74 | 8-3 | 3-0 | 7,242 | Tampa | Fla. | USF Sun Dome | ||||
| 01/13/1999 | A | Marquette | W | 78 | 63 | 9-3 | 4-0 | 11,432 | Milwaukee | Wisc. | Bradley Center | ||||
| 01/17/1999 | A | DePaul | W | 71 | 68 | 10-3 | 5-0 | 11,724 | Rosemont | Ill. | Rosemont Horizon | ||||
| 01/21/1999 | H | 5 | Cincinnati | 24 | L | 55 | 81 | 10-4 | 5-1 | 19,923 | Louisville | Ky. | Freedom Hall | ||
| 01/23/1999 | H | 13 | UCLA | 24 | L | 70 | 82 | 10-5 | 5-1 | 19,987 | Louisville | Ky. | Freedom Hall | ||
| 01/28/1999 | A | Saint Louis | L | 52 | 62 | 10-6 | 5-2 | 13,737 | St. Louis | Mo. | Kiel Center | ||||
| 01/30/1999 | H | Charlotte | L | 49 | 58 | 10-7 | 5-3 | 19,046 | Louisville | Ky. | Freedom Hall | ||||
| 02/04/1999 | H | Memphis | W | 89 | 76 | 11-7 | 6-3 | 18,021 | Louisville | Ky. | Freedom Hall | ||||
| 02/06/1999 | H | Marquette | W | 81 | 77 | 12-7 | 7-3 | 19,219 | Louisville | Ky. | Freedom Hall | ||||
| 02/11/1999 | A | Charlotte | W | 79 | 68 | 13-7 | 8-3 | 8,528 | Charlotte | N.C. | Dale F. Halton Arena | ||||
| 02/14/1999 | H | Georgia Tech | W | 78 | 58 | 14-7 | 8-3 | 19,761 | Louisville | Ky. | Freedom Hall | ||||
| 02/16/1999 | H | Houston | W | 106 | 78 | 15-7 | 9-3 | 18,859 | Louisville | Ky. | Freedom Hall | ||||
| 02/18/1999 | A | Tulane | W | 80 | 75 | 16-7 | 10-3 | 2,851 | New Orleans | La. | Fogelman Arena | ||||
| 02/21/1999 | A | 9 | Cincinnati | L | 78 | 91 | 16-8 | 10-4 | 13,176 | Cincinnati | Ohio | Shoemaker Center | |||
| 02/25/1999 | H | Alabama-Birmingham | W | 91 | 60 | 17-8 | 11-4 | 19,784 | Louisville | Ky. | Freedom Hall | ||||
| 02/27/1999 | A | Southern Mississippi | L | 58 | 59 | 17-9 | 11-5 | 3,183 | Hattiesburg | Miss. | Reed Green Coliseum | ||||
| 03/04/1999 | N | Saint Louis | W | 70 | 61 | 18-9 | 11-5 | 11,058 | Birmingham | Ala. | BJCC Arena | 1999 C-USA Tournament Quarterfinal | |||
| 03/05/1999 | A | Alabama-Birmingham | W | 77 | 68 | 19-9 | 11-5 | 12,559 | Birmingham | Ala. | BJCC Arena | 1999 C-USA Tournament Semifinal | |||
| 03/06/1999 | N | Charlotte | L | 59 | 68 | 19-10 | 11-5 | 7,404 | Birmingham | Ala. | BJCC Arena | 1999 C-USA Tournament Final | |||
| 03/11/1999 | N | Creighton | L | 58 | 62 | 19-11 | 11-5 | 10,032 | Orlando | Fla. | Orlando Arena | 1999 NCAA Tournament South Regional First Round |