36 games, 2 exhibitions
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/01/2014 | H | Barry (Exhibition) | 8 | W | 91 | 71 | 19,237 | Louisville | Ky. | KFC Yum! Center | |||||
| 11/09/2014 | H | Bellarmine (Exhibition) | 8 | W | 82 | 57 | 20,432 | Louisville | Ky. | KFC Yum! Center | |||||
| 11/14/2014 | N | Minnesota | 8 | W | 81 | 68 | 1-0 | 0-0 | 1,693 | Aguadilla | P.R. | UCSG Air Station Borinquen | 2014 Armed Forces Classic | ||
| 11/17/2014 | H | Jacksonville State | 7 | W | 88 | 39 | 2-0 | 0-0 | 20,479 | Louisville | Ky. | KFC Yum! Center | 2014 Global Sports Showcase | ||
| 11/21/2014 | H | Marshall | 7 | W | 85 | 67 | 3-0 | 0-0 | 21,661 | Louisville | Ky. | KFC Yum! Center | 2014 Global Sports Showcase | ||
| 11/24/2014 | H | Savannah State | 6 | W | 87 | 26 | 4-0 | 0-0 | 19,514 | Louisville | Ky. | KFC Yum! Center | 2014 Global Sports Showcase | ||
| 11/26/2014 | H | Cleveland State | 6 | W | 45 | 33 | 5-0 | 0-0 | 20,887 | Louisville | Ky. | KFC Yum! Center | 2014 Global Sports Showcase | ||
| 12/02/2014 | H | 14 | Ohio State | 5 | W | 64 | 55 | 6-0 | 0-0 | 22,784 | Louisville | Ky. | KFC Yum! Center | 2014 ACC-Big Ten Challenge | |
| 12/05/2014 | H | Florida International | 5 | W | 82 | 57 | 7-0 | 0-0 | 20,541 | Louisville | Ky. | KFC Yum! Center | |||
| 12/09/2014 | N | Indiana | 4 | W | 94 | 74 | 8-0 | 0-0 | 11,617 | New York | N.Y. | Madison Square Garden IV | 2014 Jimmy V Classic | ||
| 12/14/2014 | H | UNC Wilmington | 4 | W | 68 | 57 | 9-0 | 0-0 | 20,913 | Louisville | Ky. | KFC Yum! Center | 2014 Billy Minardi Classic | ||
| 12/20/2014 | A | Western Kentucky | 4 | W | 76 | 67 | 10-0 | 0-0 | 7,598 | Bowling Green | Ky. | Diddle Arena | |||
| 12/23/2014 | H | Cal State Northridge | 4 | W | 80 | 55 | 11-0 | 0-0 | 20,231 | Louisville | Ky. | KFC Yum! Center | |||
| 12/27/2014 | H | 1 | Kentucky | 4 | L | 50 | 58 | 11-1 | 0-0 | 22,812 | Louisville | Ky. | KFC Yum! Center | 2014 Basketball Hall of Fame Shootout | |
| 12/30/2014 | H | Long Beach State | 5 | W | 63 | 48 | 12-1 | 0-0 | 18,248 | Louisville | Ky. | KFC Yum! Center | |||
| 01/04/2015 | A | Wake Forest | 5 | W | 85 | 76 | 13-1 | 1-0 | 10,862 | Winston-Salem | N.C. | Lawrence Joel Veterans Memorial Coliseum | |||
| 01/07/2015 | H | Clemson | 5 | W | 58 | 52 | 14-1 | 2-0 | 21,676 | Louisville | Ky. | KFC Yum! Center | |||
| 01/10/2015 | A | 18 | North Carolina | 5 | L | 71 | 72 | 14-2 | 2-1 | 21,750 | Chapel Hill | N.C. | Dean E. Smith Center | ||
| 01/13/2015 | H | Virginia Tech | 6 | W | 78 | 63 | 15-2 | 3-1 | 21,684 | Louisville | Ky. | KFC Yum! Center | |||
| 01/17/2015 | H | 4 | Duke | 6 | L | 52 | 63 | 15-3 | 3-2 | 22,791 | Louisville | Ky. | KFC Yum! Center | ||
| 01/25/2015 | A | Pittsburgh | 10 | W | 80 | 68 | 16-3 | 4-2 | 12,508 | Pittsburgh | Pa. | Petersen Events Center | |||
| 01/28/2015 | A | Boston College | 10 | W | 81 | 72 | 17-3 | 5-2 | 5,119 | Chestnut Hill | Mass. | Conte Forum | |||
| 01/31/2015 | H | 13 | North Carolina | 10 | W | 78 | 68 | OT | 18-3 | 6-2 | 22,418 | Louisville | Ky. | KFC Yum! Center | |
| 02/03/2015 | A | Miami, Fla. | 9 | W | 63 | 55 | 19-3 | 7-2 | 6,563 | Coral Gables | Fla. | BankUnited Center | |||
| 02/07/2015 | A | 3 | Virginia | 9 | L | 47 | 52 | 19-4 | 7-3 | 14,593 | Charlottesville | Va. | John Paul Jones Arena | ||
| 02/11/2015 | H | Pittsburgh | 9 | W | 69 | 56 | 20-4 | 8-3 | 22,132 | Louisville | Ky. | KFC Yum! Center | |||
| 02/14/2015 | H | North Carolina State | 9 | L | 65 | 74 | 20-5 | 8-4 | 22,410 | Louisville | Ky. | KFC Yum! Center | |||
| 02/18/2015 | A | Syracuse | 12 | L | 59 | 69 | 20-6 | 8-5 | 26,160 | Syracuse | N.Y. | Carrier Dome | |||
| 02/21/2015 | H | Miami, Fla. | 12 | W | 55 | 53 | 21-6 | 9-5 | 21,345 | Louisville | Ky. | KFC Yum! Center | |||
| 02/23/2015 | A | Georgia Tech | 17 | W | 52 | 51 | 22-6 | 10-5 | 7,009 | Atlanta | Ga. | McCamish Pavilion | |||
| 02/28/2015 | A | Florida State | 17 | W | 81 | 59 | 23-6 | 11-5 | 8,844 | Tallahassee | Fla. | Donald L. Tucker Civic Center | |||
| 03/04/2015 | H | 12 | Notre Dame | 16 | L | 59 | 71 | 23-7 | 11-6 | 21,024 | Louisville | Ky. | KFC Yum! Center | ||
| 03/07/2015 | H | 2 | Virginia | 16 | W | 59 | 57 | 24-7 | 12-6 | 22,788 | Louisville | Ky. | KFC Yum! Center | ||
| 03/12/2015 | N | 19 | North Carolina | 14 | L | 60 | 70 | 24-8 | 12-6 | 22,026 | Greensboro | N.C. | Greensboro Coliseum | 2015 New York Life ACC Tournament Quarterfinal | |
| 03/20/2015 | N | UC Irvine | 17 | W | 57 | 55 | 25-8 | 12-6 | 14,509 | Seattle | Wash. | KeyArena | 2015 NCAA Tournament East Regional Second Round | ||
| 03/22/2015 | N | 11 | Northern Iowa | 17 | W | 66 | 53 | 26-8 | 12-6 | 14,901 | Seattle | Wash. | KeyArena | 2015 NCAA Tournament East Regional Third Round | |
| 03/27/2015 | N | North Carolina State | 17 | W | 75 | 65 | 27-8 | 12-6 | 24,453 | Syracuse | N.Y. | Carrier Dome | 2015 NCAA Tournament East Regional Semifinal | ||
| 03/29/2015 | N | 23 | Michigan State | 17 | L | 70 | 76 | OT | 27-9 | 12-6 | 24,404 | Syracuse | N.Y. | Carrier Dome | 2015 NCAA Tournament East Regional Final |