Series record: 15-6 (Home: 12-4, Away: 3-2, Neutral: 0-0)
21 games
| Date | Site | Opp AP | UL AP | W/L | UL | Opp | OT | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 10/15/1927 | H | W | 14 | 0 | Louisville | Ky. | Parkway Field | |||||
| 10/08/1932 | A | L | 0 | 105 | Murray | Ky. | College Field | |||||
| 11/04/1933 | H | L | 6 | 54 | 600 | Louisville | Ky. | Parkway Field | ||||
| 09/30/1949 | H | W | 34 | 14 | 9,000 | Louisville | Ky. | duPont Manual Stadium | ||||
| 09/19/1953 | A | W | 19 | 14 | Murray | Ky. | ||||||
| 09/18/1954 | H | L | 13 | 33 | 1,500 | Louisville | Ky. | Parkway Field | ||||
| 09/17/1955 | A | L | 14 | 33 | 5,000 | Murray | Ky. | |||||
| 10/13/1956 | H | W | 7 | 6 | 6,500 | Louisville | Ky. | Parkway Field | ||||
| 10/12/1957 | A | W | 35 | 0 | 4,000 | Murray | Ky. | Cutchin Stadium | ||||
| 10/11/1958 | H | W | 27 | 0 | 5,000 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 10/10/1959 | A | W | 28 | 0 | Murray | Ky. | Cutchin Stadium | |||||
| 10/07/1960 | H | W | 12 | 6 | 7,935 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 09/20/1980 | H | L | 9 | 13 | 23,109 | Louisville | Ky. | Fairgrounds Stadium | ||||
| 09/01/1984 | H | L | 23 | 26 | 24,557 | Louisville | Ky. | Cardinal Stadium | ||||
| 09/26/1987 | H | W | 34 | 10 | 29,231 | Louisville | Ky. | Cardinal Stadium | ||||
| 09/08/1990 | H | W | 68 | 0 | 34,417 | Louisville | Ky. | Cardinal Stadium | ||||
| 08/30/2007 | H | 10 | W | 73 | 10 | 42,185 | Louisville | Ky. | Papa John's Cardinal Stadium | |||
| 09/01/2011 | H | W | 21 | 9 | 46,157 | Louisville | Ky. | Papa John's Cardinal Stadium | ||||
| 09/06/2014 | H | 25 | W | 66 | 21 | 50,179 | Louisville | Ky. | Papa John's Cardinal Stadium | |||
| 09/30/2017 | H | 17 | W | 55 | 10 | 47,826 | Louisville | Ky. | Papa John's Cardinal Stadium | |||
| 09/07/2023 | H | W | 56 | 0 | 45,273 | Louisville | Ky. | L&N Federal Credit Union Stadium |