Series record: 9-5 (Home: 5-1, Away: 4-3, Neutral: 0-1)
14 games
| Date | Site | Opp AP | UL AP | W/L | UL | Opp | OT | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/02/1951 | H | W | 26 | 2 | 1,000 | Louisville | Ky. | duPont Manual Stadium | ||||
| 10/08/1994 | H | 18 | W | 35 | 14 | 38,318 | Louisville | Ky. | Cardinal Stadium | |||
| 09/29/2007 | A | W | 29 | 10 | 56,487 | Raleigh | N.C. | Carter-Finley Stadium | ||||
| 12/27/2011 | N | RV | L | 24 | 31 | 58,427 | Charlotte | N.C. | Bank of America Stadium | Belk Bowl | ||
| 10/18/2014 | H | RV | W | 30 | 18 | 50,227 | Louisville | Ky. | Papa John's Cardinal Stadium | |||
| 10/03/2015 | A | W | 20 | 13 | 56,417 | Raleigh | N.C. | Carter-Finley Stadium | ||||
| 10/22/2016 | H | 7 | W | 54 | 13 | 55,218 | Louisville | Ky. | Papa John's Cardinal Stadium | |||
| 10/05/2017 | A | 24 | 17 | L | 25 | 39 | 56,107 | Raleigh | N.C. | Carter-Finley Stadium | ||
| 11/17/2018 | H | L | 10 | 52 | 48,265 | Louisville | Ky. | Cardinal Stadium | ||||
| 11/16/2019 | A | W | 34 | 20 | 54,089 | Raleigh | N.C. | Carter-Finley Stadium | ||||
| 10/30/2021 | A | L | 13 | 28 | 53,123 | Raleigh | N.C. | Carter-Finley Stadium | ||||
| 11/19/2022 | H | W | 25 | 10 | 38,974 | Louisville | Ky. | Cardinal Stadium | ||||
| 09/29/2023 | A | W | 13 | 10 | 56,919 | Raleigh | N.C. | Carter-Finley Stadium | ||||
| 10/03/2026 | A | L | 28 | 31 | 56,919 | Raleigh | N.C. | Carter-Finley Stadium |