Series record: 6-7 (Home: 3-0, Away: 0-4, Neutral: 3-3)
13 games
| Date | Site | Opp AP | UL AP | W/L | UL | Opp | OT | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 03/14/1959 | N | 7 | W | 88 | 81 | 9,200 | Evanston | Ill. | McGaw Memorial Hall | 1959 NCAA Tournament Mideast Regional Final | ||
| 12/05/1992 | N | 18 | 12 | W | 73 | 69 | 9,283 | Detroit | Mich. | Joe Louis Arena | ||
| 12/04/1993 | H | 11 | W | 77 | 68 | 19,236 | Louisville | Ky. | Freedom Hall | |||
| 12/03/1994 | A | 18 | L | 71 | 85 | 15,138 | East Lansing | Mich. | Breslin Center | |||
| 12/02/1995 | H | 18 | W | 79 | 59 | 19,441 | Louisville | Ky. | Freedom Hall | |||
| 01/02/1999 | A | 13 | L | 57 | 69 | 14,659 | East Lansing | Mich. | Breslin Center | |||
| 03/29/2009 | N | 8 | 1 | L | 52 | 64 | 36,084 | Indianapolis | Ind. | Lucas Oil Stadium | 2009 NCAA Tournament Midwest Regional Final | |
| 03/22/2012 | N | 5 | 17 | W | 57 | 44 | 14,913 | Phoenix | Ariz. | US Airways Center | 2012 NCAA Tournament West Regional Semifinal | |
| 03/29/2015 | N | 23 | 17 | L | 70 | 76 | OT | 24,404 | Syracuse | N.Y. | Carrier Dome | 2015 NCAA Tournament East Regional Final |
| 12/02/2015 | A | 3 | 24 | L | 67 | 71 | 14,797 | East Lansing | Mich. | Breslin Center | 2015 Big Ten-ACC Challenge | |
| 11/27/2018 | H | 9 | W | 82 | 78 | OT | 15,477 | Louisville | Ky. | KFC Yum! Center | 2018 ACC-Big Ten Challenge | |
| 12/01/2021 | A | 22 | L | 64 | 73 | 14,797 | East Lansing | Mich. | Breslin Center | |||
| 03/21/2026 | N | 11 | 23 | L | 69 | 77 | 17,499 | Buffalo | N.Y. | KeyBank Center | 2026 NCAA Tournament Second Round |