27 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1968-11-30 | H | Georgetown College | W | 90 | 82 | 1-0 | 0-0 | 8,131 | Louisville | KY | Freedom Hall | |||
| 1968-12-04 | H | Stetson | W | 84 | 69 | 2-0 | 0-0 | 6,357 | Louisville | KY | Freedom Hall | |||
| 1968-12-07 | H | Southern Mississippi | W | 96 | 85 | 3-0 | 0-0 | 6,775 | Louisville | KY | Freedom Hall | |||
| 1968-12-11 | A | Southern Methodist | W | 79 | 73 | 4-0 | 0-0 | |||||||
| 1968-12-14 | H | Dayton | W | 84 | 69 | 5-0 | 0-0 | 12,018 | Louisville | KY | Freedom Hall | |||
| 1968-12-16 | H | Florida State | 19 | W | 79 | 78 | 6-0 | 0-0 | 7,566 | Louisville | KY | Freedom Hall | ||
| 1968-12-18 | H | Memphis | 19 | W | 67 | 66 | 7-0 | 1-0 | 8,071 | Louisville | KY | Freedom Hall | ||
| 1968-12-30 | H | North Texas State | 14 | W | 86 | 73 | 8-0 | 2-0 | 8,543 | Louisville | KY | Freedom Hall | ||
| 1969-01-02 | H | Wichita State | 14 | W | 71 | 58 | 9-0 | 3-0 | 10,398 | Louisville | KY | Freedom Hall | ||
| 1969-01-04 | A | Tulsa | 14 | L | 69 | 85 | 9-1 | 3-1 | Tulsa | OK | Tulsa Fairgrounds Pavilion | |||
| 1969-01-06 | A | Saint Louis | 14 | W | 81 | 80 | 10-1 | 4-1 | 2,290 | St. Louis | MO | |||
| 1969-01-11 | A | 19 | Cincinnati | 14 | L | 75 | 87 | 10-2 | 4-2 | |||||
| 1969-01-15 | A | Dayton | L | 67 | 69 | 10-3 | 4-2 | |||||||
| 1969-01-25 | H | Drake | W | 84 | 70 | 11-3 | 5-2 | 6,987 | Louisville | KY | Freedom Hall | |||
| 1969-02-01 | H | Bradley | W | 77 | 64 | 12-3 | 6-2 | 10,340 | Louisville | KY | Freedom Hall | |||
| 1969-02-06 | A | Memphis | W | 60 | 51 | 13-3 | 7-2 | |||||||
| 1969-02-08 | A | North Texas State | W | 78 | 75 | 14-3 | 8-2 | |||||||
| 1969-02-13 | H | 7 | Tulsa | 20 | W | 83 | 81 | 15-3 | 9-2 | 15,047 | Louisville | KY | Freedom Hall | |
| 1969-02-15 | A | Wichita State | 20 | W | 65 | 62 | 16-3 | 10-2 | ||||||
| 1969-02-22 | H | Cincinnati | 13 | W | 72 | 68 | 17-3 | 11-2 | 17,661 | Louisville | KY | Freedom Hall | ||
| 1969-02-26 | H | Saint Louis | 11 | W | 93 | 67 | 18-3 | 12-2 | 10,619 | Louisville | KY | Freedom Hall | ||
| 1969-03-01 | A | Drake | 11 | L | 67 | 101 | 18-4 | 12-3 | Des Moines | IA | Veterans Memorial Auditorium | |||
| 1969-03-03 | H | Bellarmine | 15 | W | 93 | 80 | 19-4 | 12-3 | 9,863 | Louisville | KY | Freedom Hall | ||
| 1969-03-06 | A | Bradley | 15 | W | 82 | 78 | 20-4 | 13-3 | ||||||
| 1969-03-10 | N | 11 | Drake | 15 | L | 73 | 77 | 20-5 | 13-3 | Wichita | KS | 1969 MVC Playoff | ||
| 1969-03-16 | N | Fordham | 15 | W | 73 | 70 | 21-5 | 13-3 | New York | NY | Madison Square Garden IV | 1969 NIT | ||
| 1969-03-18 | N | 16 | Boston College | 15 | L | 83 | 88 | 21-6 | 13-3 | New York | NY | Madison Square Garden IV | 1969 NIT |