8 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 10/08/1927 | H | Transylvania | W | 25 | 6 | 1-0 | 1-0 | Louisville | Ky. | Parkway Field | |||||
| 10/15/1927 | H | Murray State | W | 14 | 0 | 2-0 | 1-0 | Louisville | Ky. | Parkway Field | |||||
| 10/22/1927 | A | Marshall | L | 6 | 37 | 2-1 | 1-0 | Huntington | W.Va. | ||||||
| 10/29/1927 | H | Centre | W | 40 | 7 | 3-1 | 2-0 | Louisville | Ky. | Parkway Field | |||||
| 11/05/1927 | A | Western Kentucky | L | 6 | 7 | 3-2 | 2-1 | Bowling Green | Ky. | ||||||
| 11/12/1927 | A | Eastern Kentucky | W | 21 | 13 | 4-2 | 3-1 | Richmond | Ky. | ||||||
| 11/19/1927 | H | Davis & Elkins | L | 0 | 32 | 4-3 | 3-1 | Louisville | Ky. | Parkway Field | |||||
| 11/24/1927 | A | Centenary | L | 2 | 59 | 4-4 | 3-1 | 7,000 | Shreveport | La. |