8 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/19/1953 | A | Murray State | W | 19 | 14 | 1-0 | Murray | Ky. | |||||||
| 10/03/1953 | A | Florida State | L | 0 | 59 | 1-1 | 9,000 | Tallahassee | Fla. | Doak Campbell Stadium | |||||
| 10/10/1953 | H | Xavier | L | 13 | 19 | 1-2 | 4,500 | Louisville | Ky. | Parkway Field | |||||
| 10/17/1953 | A | Dayton | L | 13 | 20 | 1-3 | 7,000 | Dayton | Ohio | University of Dayton Stadium | |||||
| 10/24/1953 | A | Tennessee | L | 6 | 59 | 1-4 | 15,000 | Knoxville | Tenn. | Shields-Watkins Field | |||||
| 10/30/1953 | A | Chattanooga | L | 6 | 44 | 1-5 | 4,000 | Chattanooga | Tenn. | Chamberlain Field | |||||
| 11/07/1953 | H | Cincinnati | L | 0 | 41 | 1-6 | 3,500 | Louisville | Ky. | Parkway Field | |||||
| 11/14/1953 | H | Eastern Kentucky | L | 13 | 20 | 1-7 | 2,500 | Louisville | Ky. | Parkway Field |