11 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 08/30/1997 | A | Kentucky | L | 24 | 38 | 0-1 | 59,186 | Lexington | Ky. | Commonwealth Stadium | |||||
| 09/06/1997 | H | Utah | L | 21 | 27 | 0-2 | 35,437 | Louisville | Ky. | Cardinal Stadium | |||||
| 09/13/1997 | H | Illinois | W | 26 | 14 | 1-2 | 36,824 | Louisville | Ky. | Cardinal Stadium | |||||
| 09/20/1997 | H | 1 | Penn State | L | 21 | 57 | 1-3 | 39,826 | Louisville | Ky. | Cardinal Stadium | ||||
| 09/27/1997 | A | Oklahoma | L | 14 | 35 | 1-4 | 74,993 | Norman | Okla. | Oklahoma Memorial Stadium | |||||
| 10/04/1997 | A | Southern Mississippi | L | 24 | 42 | 1-5 | 0-1 | 23,028 | Hattiesburg | Miss. | |||||
| 10/11/1997 | H | Tulane | L | 33 | 64 | 1-6 | 0-2 | 29,547 | Louisville | Ky. | Cardinal Stadium | ||||
| 10/25/1997 | H | Houston | L | 22 | 36 | 1-7 | 0-3 | 21,432 | Louisville | Ky. | Cardinal Stadium | ||||
| 11/01/1997 | H | East Carolina | L | 31 | 45 | 1-8 | 0-4 | 12,850 | Louisville | Ky. | Cardinal Stadium | ||||
| 11/08/1997 | A | Cincinnati | L | 9 | 28 | 1-9 | 0-5 | 21,346 | Cincinnati | Ohio | Nippert Stadium | ||||
| 11/15/1997 | A | Memphis | L | 20 | 21 | 1-10 | 0-6 | 15,243 | Memphis | Tenn. | Liberty Bowl Memorial Stadium |