13 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Stadium | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 09/01/2002 | H | Kentucky | 17 | L | 17 | 22 | 0-1 | 42,660 | Louisville | Ky. | Papa John's Cardinal Stadium | ||||
| 09/07/2002 | A | Duke | RV | W | 40 | 3 | 1-1 | 25,486 | Durham | N.C. | Wallace Wade Stadium | ||||
| 09/14/2002 | A | 24 | Colorado State | RV | L | 33 | 36 | 1-2 | 31,607 | Fort Collins | Colo. | Hughes Stadium | |||
| 09/21/2002 | A | Army | W | 45 | 14 | 2-2 | 1-0 | 28,625 | West Point | N.Y. | Michie Stadium | ||||
| 09/26/2002 | H | 4 | Florida State | W | 26 | 20 | OT | 3-2 | 1-0 | 38,109 | Louisville | Ky. | Papa John's Cardinal Stadium | ||
| 10/08/2002 | A | Memphis | RV | W | 38 | 32 | 4-2 | 2-0 | 44,081 | Memphis | Tenn. | Liberty Bowl Memorial Stadium | |||
| 10/19/2002 | H | Texas Christian | RV | L | 31 | 45 | 4-3 | 2-1 | 34,127 | Louisville | Ky. | Papa John's Cardinal Stadium | |||
| 10/26/2002 | H | East Carolina | W | 44 | 20 | 5-3 | 3-1 | 32,428 | Louisville | Ky. | Papa John's Cardinal Stadium | ||||
| 11/07/2002 | H | Cincinnati | L | 14 | 24 | 5-4 | 3-2 | 36,253 | Louisville | Ky. | Papa John's Cardinal Stadium | ||||
| 11/14/2002 | A | Southern Mississippi | W | 20 | 17 | 2 OT | 6-4 | 4-2 | 28,076 | Hattiesburg | Miss. | M. M. Roberts Stadium | |||
| 11/23/2002 | H | Alabama-Birmingham | W | 41 | 21 | 7-4 | 5-2 | 35,261 | Louisville | Ky. | Papa John's Cardinal Stadium | ||||
| 11/30/2002 | A | Houston | L | 10 | 27 | 7-5 | 5-3 | 11,048 | Houston | Texas | Robertson Stadium | ||||
| 12/18/2002 | N | RV | Marshall | L | 15 | 38 | 7-6 | 5-3 | 40,646 | Mobile | Ala. | Ladd Peebles Stadium | GMAC Bowl |