Series record: 6-12 (Home: 4-4, Away: 1-6, Neutral: 1-2)
18 games
| Date | Site | Opp AP | UL AP | W/L | UL | Opp | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1945-12-08 | H | L | 51 | 55 | Louisville | KY | |||||
| 1945-12-19 | A | L | 45 | 51 | |||||||
| 1951-12-15 | A | 17 | L | 65 | 82 | ||||||
| 1952-12-08 | H | W | 89 | 85 | Louisville | KY | |||||
| 1976-12-11 | A | 14 | L | 70 | 72 | 14,123 | West Lafayette | IN | Mackey Arena | ||
| 1977-12-13 | H | 17 | 10 | W | 68 | 66 | 16,433 | Louisville | KY | Freedom Hall | |
| 1981-12-09 | A | 3 | W | 73 | 71 | 14,122 | West Lafayette | IN | Mackey Arena | ||
| 1982-12-04 | H | 7 | L | 63 | 69 | 16,613 | Louisville | KY | Freedom Hall | ||
| 1983-11-30 | A | L | 83 | 90 | 13,356 | ||||||
| 1985-12-07 | H | 16 | W | 77 | 58 | 19,265 | Louisville | KY | Freedom Hall | ||
| 1987-01-18 | A | 6 | L | 73 | 88 | 14,123 | West Lafayette | IN | Mackey Arena | ||
| 1988-01-23 | H | 5 | L | 85 | 91 | 19,553 | Louisville | KY | Freedom Hall | ||
| 1996-12-14 | N | 22 | W | 88 | 72 | 12,646 | Indianapolis | IN | Market Square Arena | ||
| 1997-12-06 | H | 6 | L | 69 | 87 | 19,976 | Louisville | KY | Freedom Hall | ||
| 2002-11-30 | N | L | 84 | 86 | 18,345 | Indianapolis | IN | Conseco Fieldhouse | 2002 John Wooden Tradition | ||
| 2007-12-15 | N | 22 | L | 59 | 67 | 17,170 | Indianapolis | IN | Conseco Fieldhouse | 2007 John Wooden Tradition | |
| 2016-11-30 | H | 15 | 14 | W | 71 | 64 | 21,841 | Louisville | KY | KFC Yum! Center | 2016 ACC-Big Ten Challenge |
| 2017-11-28 | A | 17 | L | 57 | 66 | 14,804 | West Lafayette | IN | Mackey Arena | 2017 Big Ten-ACC Challenge |