14 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1922-01-14 | H | Franklin | L | 13 | 28 | 0-1 | Louisville | KY | ||||||
| 1922-01-17 | H | Kentucky | L | 14 | 38 | 0-2 | Louisville | KY | St. Xavier Gymnasium | |||||
| 1922-01-20 | A | Georgetown College | L | 12 | 26 | 0-3 | ||||||||
| 1922-01-21 | A | Kentucky | L | 22 | 29 | 0-4 | Lexington | KY | ||||||
| 1922-01-27 | A | Cumberland | L | 19 | 30 | 0-5 | ||||||||
| 1922-01-28 | A | Chattanooga | L | 8 | 34 | 0-6 | ||||||||
| 1922-02-03 | H | Georgetown College | L | 14 | 18 | 0-7 | Louisville | KY | St. Xavier Gymnasium | |||||
| 1922-02-11 | H | Cumberland | L | 13 | 19 | 0-8 | Louisville | KY | St. Xavier Gymnasium | |||||
| 1922-02-14 | A | Centre | L | 12 | 25 | 0-9 | ||||||||
| 1922-02-16 | A | Tennessee | L | 22 | 28 | 0-10 | ||||||||
| 1922-02-18 | H | Transylvania | W | 23 | 12 | 1-10 | Louisville | KY | YMCA Gymnasium | |||||
| 1922-02-25 | A | Louisville YMHA | L | 15 | 27 | 1-11 | Louisville | KY | YMHA Gymnasium | |||||
| 1922-03-01 | H | Rose Poly | L | 19 | 38 | 1-12 | Louisville | KY | St. Xavier Gymnasium | |||||
| 1922-03-04 | H | Centre | L | 18 | 27 | 1-13 | Louisville | KY | YMCA Gymnasium |