Series record: 18-40 (Home: 11-14, Away: 5-22, Neutral: 2-4)
58 games
| Date | Site | Opp AP | UL AP | W/L | UL | Opp | OT | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 02/15/1913 | A | L | 10 | 34 | Lexington | Ky. | ||||||
| 02/07/1914 | A | L | 17 | 22 | Lexington | Ky. | ||||||
| 03/03/1914 | H | L | 13 | 26 | Louisville | Ky. | Tharp University School Gymnasium | |||||
| 01/23/1915 | A | L | 14 | 18 | Lexington | Ky. | ||||||
| 02/27/1915 | H | W | 26 | 15 | Louisville | Ky. | YMCA Gymnasium | |||||
| 02/12/1916 | A | W | 26 | 22 | Lexington | Ky. | ||||||
| 02/22/1916 | H | L | 24 | 32 | Louisville | Ky. | YMCA Gymnasium | |||||
| 01/17/1922 | H | L | 14 | 38 | Louisville | Ky. | St. Xavier Gymnasium | |||||
| 01/21/1922 | A | L | 22 | 29 | Lexington | Ky. | ||||||
| 03/27/1948 | N | L | 57 | 91 | New York | N.Y. | Madison Square Garden III | 1948 Olympic Trials | ||||
| 03/20/1951 | N | 1 | L | 68 | 79 | Raleigh | N.C. | Reynolds Coliseum | 1951 NCAA Tournament East Regional First Round | |||
| 03/13/1959 | N | 2 | W | 76 | 61 | 9,200 | Evanston | Ill. | McGaw Memorial Hall | 1959 NCAA Tournament Mideast Regional Semifinal | ||
| 03/26/1983 | N | 12 | 2 | W | 80 | 68 | OT | 12,489 | Knoxville | Tenn. | Stokely Center | 1983 NCAA Tournament Mideast Regional Final |
| 11/26/1983 | A | 2 | 6 | L | 44 | 65 | 24,012 | Lexington | Ky. | Rupp Arena | ||
| 03/22/1984 | A | 3 | L | 67 | 72 | 23,525 | Lexington | Ky. | Rupp Arena | 1984 NCAA Tournament Mideast Regional Semifinal | ||
| 12/15/1984 | H | 14 | W | 71 | 64 | 19,487 | Louisville | Ky. | Freedom Hall | |||
| 12/28/1985 | A | 13 | 15 | L | 64 | 69 | 24,180 | Lexington | Ky. | Rupp Arena | ||
| 12/27/1986 | H | 18 | L | 51 | 85 | 19,513 | Louisville | Ky. | Freedom Hall | |||
| 12/12/1987 | A | 1 | L | 75 | 76 | 23,489 | Lexington | Ky. | Rupp Arena | |||
| 12/31/1988 | H | 14 | W | 97 | 75 | 19,502 | Louisville | Ky. | Freedom Hall | |||
| 12/30/1989 | A | 8 | W | 86 | 79 | 24,089 | Lexington | Ky. | Rupp Arena | |||
| 12/29/1990 | H | 18 | L | 85 | 93 | 19,589 | Louisville | Ky. | Freedom Hall | |||
| 12/28/1991 | A | 17 | 21 | L | 89 | 103 | 24,295 | Lexington | Ky. | Rupp Arena | ||
| 12/12/1992 | H | 3 | 9 | L | 68 | 88 | 19,663 | Louisville | Ky. | Freedom Hall | ||
| 11/27/1993 | A | 2 | 7 | L | 70 | 78 | 24,327 | Lexington | Ky. | Rupp Arena | ||
| 01/01/1995 | H | 5 | W | 88 | 86 | 19,841 | Louisville | Ky. | Freedom Hall | |||
| 12/23/1995 | A | 4 | 25 | L | 66 | 89 | 24,340 | Lexington | Ky. | Rupp Arena | ||
| 12/31/1996 | H | 3 | 14 | L | 54 | 74 | 20,075 | Louisville | Ky. | Freedom Hall | ||
| 12/27/1997 | A | 4 | W | 79 | 76 | 24,303 | Lexington | Ky. | Rupp Arena | |||
| 12/26/1998 | H | 3 | W | 83 | 74 | 20,051 | Louisville | Ky. | Freedom Hall | |||
| 12/18/1999 | A | L | 46 | 76 | 23,491 | Lexington | Ky. | Rupp Arena | ||||
| 01/02/2001 | H | L | 62 | 64 | 20,061 | Louisville | Ky. | Freedom Hall | ||||
| 12/29/2001 | A | 6 | L | 62 | 82 | 24,330 | Lexington | Ky. | Rupp Arena | |||
| 12/28/2002 | H | 14 | W | 81 | 63 | 20,061 | Louisville | Ky. | Freedom Hall | |||
| 12/27/2003 | A | 2 | 20 | W | 65 | 56 | 24,328 | Lexington | Ky. | Rupp Arena | ||
| 12/18/2004 | H | 9 | 13 | L | 58 | 60 | 20,088 | Louisville | Ky. | Freedom Hall | ||
| 12/17/2005 | A | 23 | 4 | L | 61 | 73 | 24,432 | Lexington | Ky. | Rupp Arena | ||
| 12/16/2006 | H | L | 49 | 61 | 20,042 | Louisville | Ky. | Freedom Hall | ||||
| 01/05/2008 | A | W | 89 | 75 | 24,386 | Lexington | Ky. | Rupp Arena | ||||
| 01/04/2009 | H | 18 | W | 74 | 71 | 20,078 | Louisville | Ky. | Freedom Hall | |||
| 01/02/2010 | A | 3 | L | 62 | 71 | 24,479 | Lexington | Ky. | Rupp Arena | |||
| 12/31/2010 | H | 11 | 22 | L | 63 | 78 | 22,803 | Louisville | Ky. | KFC Yum! Center | ||
| 12/31/2011 | A | 3 | 4 | L | 62 | 69 | 24,387 | Lexington | Ky. | Rupp Arena | ||
| 03/31/2012 | N | 1 | 17 | L | 61 | 69 | 73,361 | New Orleans | La. | Mercedes-Benz Superdome | 2012 NCAA Tournament Semifinal | |
| 12/29/2012 | H | 4 | W | 80 | 77 | 22,810 | Louisville | Ky. | KFC Yum! Center | |||
| 12/28/2013 | A | 18 | 6 | L | 66 | 73 | 24,396 | Lexington | Ky. | Rupp Arena | ||
| 03/28/2014 | N | 5 | L | 69 | 74 | 41,072 | Indianapolis | Ind. | Lucas Oil Stadium | 2014 NCAA Tournament Midwest Regional Semifinal | ||
| 12/27/2014 | H | 1 | 4 | L | 50 | 58 | 22,812 | Louisville | Ky. | KFC Yum! Center | 2014 Basketball Hall of Fame Shootout | |
| 12/26/2015 | A | 12 | 16 | L | 73 | 75 | 24,412 | Lexington | Ky. | Rupp Arena | ||
| 12/21/2016 | H | 6 | 10 | W | 73 | 70 | 22,783 | Louisville | Ky. | KFC Yum! Center | ||
| 12/29/2017 | A | 16 | L | 61 | 90 | 24,228 | Lexington | Ky. | Rupp Arena | |||
| 12/29/2018 | H | 16 | L | 58 | 71 | 20,882 | Louisville | Ky. | KFC Yum! Center | |||
| 12/28/2019 | A | 19 | 3 | L | 70 | 78 | OT | 20,437 | Louisville | Ky. | Rupp Arena | |
| 12/26/2020 | H | W | 62 | 59 | 3,281 | Louisville | Ky. | KFC Yum! Center | ||||
| 12/31/2022 | A | 19 | L | 63 | 86 | 20,934 | Lexington | Ky. | Rupp Arena | |||
| 12/21/2023 | H | 9 | L | 76 | 95 | 17,293 | Louisville | Ky. | KFC Yum! Center | |||
| 12/14/2024 | A | 5 | L | 85 | 93 | 21,093 | Lexington | Ky. | Rupp Arena | |||
| 11/11/2025 | H | 9 | 12 | W | 96 | 88 | 22,586 | Louisville | Ky. | KFC Yum! Center |