28 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | OT | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 11/23/1945 | N | Indiana State | W | 60 | 39 | 1-0 | Jeffersonville | Ind. | Jeffersonville Fieldhouse | 1945 OVC Preseason Tournament | |||||
| 11/24/1945 | N | Morehead State | W | 55 | 41 | 2-0 | Jeffersonville | Ind. | Jeffersonville Fieldhouse | 1945 OVC Preseason Tournament | |||||
| 11/24/1945 | N | Western Kentucky | W | 51 | 45 | 3-0 | Jeffersonville | Ind. | Jeffersonville Fieldhouse | 1945 OVC Preseason Tournament | |||||
| 11/28/1945 | H | Kentucky Wesleyan | W | 83 | 47 | 4-0 | 1-0 | Louisville | Ky. | ||||||
| 12/01/1945 | H | Murray State | W | 52 | 42 | 5-0 | 2-0 | Louisville | Ky. | ||||||
| 12/05/1945 | A | Evansville | W | 51 | 42 | 6-0 | 2-0 | ||||||||
| 12/08/1945 | H | Purdue | L | 51 | 55 | 6-1 | 2-0 | Louisville | Ky. | ||||||
| 12/11/1945 | A | Georgetown College | W | 80 | 23 | 7-1 | 3-0 | ||||||||
| 12/15/1945 | H | Indiana | L | 59 | 62 | 7-2 | 3-0 | Louisville | Ky. | ||||||
| 12/18/1945 | A | Butler | W | 51 | 41 | 8-2 | 3-0 | ||||||||
| 12/19/1945 | A | Purdue | L | 45 | 51 | 8-3 | 3-0 | ||||||||
| 01/05/1946 | H | Vanderbilt | W | 60 | 27 | 9-3 | 3-0 | Louisville | Ky. | ||||||
| 01/07/1946 | A | Kentucky Wesleyan | W | 71 | 50 | 4-0 | |||||||||
| 01/08/1946 | A | Morehead State | W | 44 | 39 | 11-3 | 5-0 | ||||||||
| 01/12/1946 | H | Cincinnati | W | 59 | 41 | 12-3 | 5-0 | Louisville | Ky. | ||||||
| 01/16/1946 | H | Georgetown College | W | 82 | 47 | 13-3 | 6-0 | Louisville | Ky. | ||||||
| 01/19/1946 | H | Eastern Kentucky | W | 71 | 38 | 14-3 | 7-0 | Louisville | Ky. | ||||||
| 01/22/1946 | A | Cincinnati | W | 61 | 39 | 15-3 | 7-0 | ||||||||
| 01/26/1946 | A | Murray State | L | 44 | 54 | 15-4 | 7-1 | ||||||||
| 01/30/1946 | H | Evansville | W | 76 | 45 | 16-4 | 7-1 | Louisville | Ky. | ||||||
| 02/02/1946 | H | Western Kentucky | W | 64 | 51 | 17-4 | 8-1 | Louisville | Ky. | ||||||
| 02/06/1946 | A | Eastern Kentucky | L | 49 | 60 | 17-5 | 8-2 | ||||||||
| 02/11/1946 | H | Butler | W | 79 | 33 | 18-5 | 8-2 | Louisville | Ky. | ||||||
| 02/13/1946 | A | Western Kentucky | W | 65 | 54 | 19-5 | 9-2 | ||||||||
| 02/16/1946 | H | Morehead State | W | 61 | 50 | 20-5 | 10-2 | Louisville | Ky. | ||||||
| 02/22/1946 | H | Western Kentucky | W | 50 | 43 | 21-5 | 10-2 | Louisville | Ky. | 1946 KIAC Tournament | |||||
| 02/23/1946 | H | Murray State | W | 60 | 56 | 22-5 | 10-2 | Louisville | Ky. | 1946 KIAC Tournament | |||||
| 02/23/1946 | H | Eastern Kentucky | L | 51 | 66 | 22-6 | 10-2 | Louisville | Ky. | 1946 KIAC Tournament |