25 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1957-12-02 | A | Evansville | L | 82 | 92 | 0-1 | 4,305 | Evansville | IN | |||||
| 1957-12-05 | H | Georgetown College | W | 74 | 54 | 1-1 | 3,738 | Louisville | KY | Freedom Hall | ||||
| 1957-12-07 | H | Alabama | W | 80 | 72 | 2-1 | 6,736 | Louisville | KY | Freedom Hall | ||||
| 1957-12-12 | A | Iona | W | 89 | 65 | 3-1 | 7,000 | New York | NY | Madison Square Garden III | ||||
| 1957-12-14 | A | Detroit Mercy | L | 64 | 68 | 3-2 | 3,447 | Detroit | MI | |||||
| 1957-12-18 | H | Marquette | W | 73 | 65 | 4-2 | 3,910 | Louisville | KY | Freedom Hall | ||||
| 1957-12-20 | H | Army | W | 66 | 61 | 5-2 | 7,750 | Louisville | KY | Freedom Hall | 1957 Bluegrass Invitational | |||
| 1957-12-21 | H | 7 | San Francisco | L | 55 | 62 | 5-3 | 7,800 | Louisville | KY | Freedom Hall | 1957 Bluegrass Invitational | ||
| 1958-01-01 | A | Murray State | L | 61 | 75 | 5-4 | 2,954 | Murray | KY | |||||
| 1958-01-04 | A | Xavier | L | 80 | 82 | 5-5 | 4,158 | Cincinnati | OH | Cincinnati Gardens | ||||
| 1958-01-08 | H | Saint Louis | W | 67 | 55 | 6-5 | 4,476 | Louisville | KY | Freedom Hall | ||||
| 1958-01-11 | A | Marquette | L | 79 | 85 | 6-6 | 4,570 | Milwaukee | WI | Milwaukee Arena | ||||
| 1958-01-13 | A | DePaul | L | 60 | 62 | 6-7 | 1,047 | Chicago | IL | |||||
| 1958-01-18 | H | Notre Dame | W | 94 | 83 | 7-7 | 8,200 | Louisville | KY | Freedom Hall | ||||
| 1958-01-25 | H | 17 | Dayton | L | 49 | 57 | 7-8 | 10,425 | Louisville | KY | Freedom Hall | |||
| 1958-01-29 | A | Notre Dame | L | 53 | 73 | 7-9 | 3,800 | Notre Dame | IN | |||||
| 1958-02-01 | H | Kentucky Wesleyan | W | 86 | 74 | 8-9 | 4,242 | Louisville | KY | Freedom Hall | ||||
| 1958-02-05 | A | Eastern Kentucky | L | 62 | 75 | 8-10 | 2,500 | Richmond | KY | |||||
| 1958-02-08 | H | Xavier | W | 76 | 74 | 9-10 | 5,208 | Louisville | KY | Freedom Hall | ||||
| 1958-02-12 | H | Detroit Mercy | W | 76 | 58 | 10-10 | 3,406 | Louisville | KY | Freedom Hall | ||||
| 1958-02-15 | H | Murray State | W | 72 | 58 | 11-10 | 3,695 | Louisville | KY | Freedom Hall | ||||
| 1958-02-19 | A | Kentucky Wesleyan | L | 69 | 83 | 11-11 | 4,200 | Owensboro | KY | Owensboro Sportscenter | ||||
| 1958-02-22 | A | 11 | Dayton | L | 52 | 58 | 11-12 | 5,803 | Dayton | OH | Dayton Fieldhouse | |||
| 1958-02-26 | H | DePaul | W | 73 | 55 | 12-12 | 3,354 | Louisville | KY | Freedom Hall | ||||
| 1958-03-03 | H | Eastern Kentucky | W | 78 | 55 | 13-12 | 4,001 | Louisville | KY | Freedom Hall |