26 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1959-12-01 | H | Furman | W | 87 | 68 | 1-0 | 6,000 | Louisville | KY | Freedom Hall | ||||
| 1959-12-05 | A | Georgia Tech | L | 56 | 68 | 1-1 | Atlanta | GA | Alexander Coliseum | |||||
| 1959-12-07 | A | Furman | W | 77 | 61 | 2-1 | ||||||||
| 1959-12-10 | H | Eastern Kentucky | W | 75 | 67 | 3-1 | 5,500 | Louisville | KY | Freedom Hall | ||||
| 1959-12-12 | H | Davidson | W | 90 | 47 | 4-1 | 3,316 | Louisville | KY | Freedom Hall | ||||
| 1959-12-19 | H | Cincinnati | L | 74 | 97 | 4-2 | 16,500 | Louisville | KY | Freedom Hall | ||||
| 1959-12-21 | H | Alabama | W | 84 | 54 | 5-2 | 3,822 | Louisville | KY | Freedom Hall | ||||
| 1959-12-23 | H | Wittenberg | W | 59 | 46 | 6-2 | Louisville | KY | Freedom Hall | |||||
| 1959-12-28 | H | Fordham | W | 66 | 61 | 7-2 | 6,529 | Louisville | KY | Freedom Hall | 1959 Bluegrass Invitational | |||
| 1959-12-29 | H | 7 | Indiana | L | 71 | 90 | 7-3 | 9,009 | Louisville | KY | Freedom Hall | 1959 Bluegrass Invitational | ||
| 1960-01-02 | A | 20 | DePaul | W | 75 | 74 | 8-3 | IL | ||||||
| 1960-01-09 | A | Marquette | L | 57 | 61 | 8-4 | ||||||||
| 1960-01-16 | H | Xavier | W | 84 | 62 | 9-4 | 7,516 | Louisville | KY | Freedom Hall | ||||
| 1960-01-20 | H | Murray State | W | 78 | 72 | 10-4 | Louisville | KY | Freedom Hall | |||||
| 1960-01-23 | A | 19 | Dayton | L | 53 | 62 | 10-5 | |||||||
| 1960-01-30 | H | Kentucky Wesleyan | W | 86 | 71 | 11-5 | Louisville | KY | Freedom Hall | |||||
| 1960-02-03 | A | Kentucky Wesleyan | W | 80 | 72 | 12-5 | ||||||||
| 1960-02-06 | A | Xavier | L | 64 | 75 | 12-6 | ||||||||
| 1960-02-10 | H | Marquette | L | 70 | 78 | 12-7 | Louisville | KY | Freedom Hall | |||||
| 1960-02-13 | H | DePaul | L | 76 | 85 | 12-8 | Louisville | KY | Freedom Hall | |||||
| 1960-02-20 | H | Dayton | W | 80 | 55 | 13-8 | Louisville | KY | Freedom Hall | |||||
| 1960-02-24 | A | Murray State | W | 74 | 67 | 14-8 | ||||||||
| 1960-02-27 | N | Notre Dame | L | 54 | 65 | 14-9 | Chicago | IL | Chicago Stadium | |||||
| 1960-02-29 | H | Miami, Ohio | W | 83 | 65 | 15-9 | Louisville | KY | Freedom Hall | |||||
| 1960-03-03 | A | Eastern Kentucky | L | 63 | 81 | 15-10 | ||||||||
| 1960-03-07 | H | 13 | Saint Louis | L | 60 | 66 | 15-11 | Louisville | KY | Freedom Hall |