30 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1972-11-30 | H | Vanderbilt | 20 | L | 57 | 66 | 0-1 | 0-0 | 5,069 | Louisville | KY | Louisville Convention Center | ||
| 1972-12-02 | H | Georgetown College | 20 | W | 66 | 57 | 1-1 | 0-0 | 6,876 | Louisville | KY | Freedom Hall | ||
| 1972-12-05 | H | Dayton | W | 75 | 58 | 2-1 | 0-0 | 7,544 | Louisville | KY | Freedom Hall | |||
| 1972-12-09 | H | Butler | W | 90 | 67 | 3-1 | 0-0 | 8,180 | Louisville | KY | Freedom Hall | |||
| 1972-12-18 | H | Navy | W | 68 | 52 | 4-1 | 0-0 | 7,729 | Louisville | KY | Freedom Hall | |||
| 1972-12-20 | H | Florida | W | 69 | 57 | 5-1 | 0-0 | 8,221 | Louisville | KY | Freedom Hall | |||
| 1972-12-23 | A | Utah | W | 84 | 67 | 6-1 | 0-0 | |||||||
| 1972-12-27 | N | Fordham | W | 100 | 73 | 7-1 | 0-0 | Honolulu | HI | Neal S. Blaisdell Arena | 1972 Rainbow Classic | |||
| 1972-12-29 | A | Hawaii | W | 95 | 82 | 8-1 | 0-0 | Honolulu | HI | Neal S. Blaisdell Arena | 1972 Rainbow Classic | |||
| 1972-12-30 | N | 11 | North Carolina | L | 86 | 89 | 8-2 | 0-0 | Honolulu | HI | Neal S. Blaisdell Arena | 1972 Rainbow Classic | ||
| 1973-01-04 | H | North Texas State | W | 76 | 69 | 9-2 | 1-0 | 11,115 | Louisville | KY | Freedom Hall | |||
| 1973-01-06 | H | Detroit Mercy | W | 76 | 58 | 10-2 | 1-0 | 10,095 | Louisville | KY | Freedom Hall | |||
| 1973-01-13 | A | Wichita State | 20 | W | 78 | 75 | 11-2 | 2-0 | ||||||
| 1973-01-17 | A | Dayton | 20 | W | 74 | 73 | 12-2 | 2-0 | ||||||
| 1973-01-20 | A | Saint Louis | 20 | L | 51 | 61 | 12-3 | 2-1 | ||||||
| 1973-01-25 | A | 17 | Memphis | L | 76 | 81 | 12-4 | 2-2 | ||||||
| 1973-01-27 | A | North Texas State | L | 64 | 78 | 12-5 | 2-3 | |||||||
| 1973-01-29 | H | New Mexico State | W | 91 | 64 | 13-5 | 3-3 | 7,637 | Louisville | KY | Freedom Hall | |||
| 1973-02-01 | H | Bradley | W | 91 | 74 | 14-5 | 4-3 | 8,570 | Louisville | KY | Freedom Hall | |||
| 1973-02-03 | H | Saint Louis | W | 88 | 49 | 15-5 | 5-3 | 7,756 | Louisville | KY | Freedom Hall | |||
| 1973-02-05 | A | Cincinnati | L | 79 | 81 | 15-6 | 5-3 | |||||||
| 1973-02-08 | H | 15 | Memphis | W | 83 | 69 | 16-6 | 6-3 | 14,056 | Louisville | KY | Freedom Hall | ||
| 1973-02-15 | A | Drake | W | 80 | 77 | 17-6 | 7-3 | Des Moines | IA | Veterans Memorial Auditorium | ||||
| 1973-02-17 | A | Bradley | W | 84 | 78 | 18-6 | 8-3 | |||||||
| 1973-02-22 | A | West Texas State | W | 85 | 70 | 19-6 | 9-3 | Amarillo | TX | Amarillo Civic Center Coliseum | ||||
| 1973-02-24 | H | Cincinnati | W | 91 | 81 | 20-6 | 9-3 | 12,653 | Louisville | KY | Freedom Hall | |||
| 1973-03-01 | H | Tulsa | W | 69 | 62 | 21-6 | 10-3 | 12,597 | Louisville | KY | Freedom Hall | |||
| 1973-03-03 | H | Drake | W | 66 | 60 | 22-6 | 11-3 | 11,609 | Louisville | KY | Freedom Hall | |||
| 1973-03-17 | N | American | W | 97 | 84 | 23-6 | 11-3 | 15,236 | New York | NY | Madison Square Garden IV | 1973 NIT | ||
| 1973-03-20 | N | Notre Dame | L | 71 | 79 | 23-7 | 11-3 | 9,388 | New York | NY | Madison Square Garden IV | 1973 NIT |