26 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1951-12-01 | H | Kentucky Wesleyan | W | 61 | 50 | 1-0 | Louisville | KY | ||||||
| 1951-12-05 | A | Dayton | W | 79 | 76 | 2-0 | 7,000 | Dayton | OH | Dayton Fieldhouse | ||||
| 1951-12-08 | H | Marquette | W | 76 | 63 | 3-0 | Louisville | KY | ||||||
| 1951-12-10 | H | Georgetown College | 17 | W | 92 | 36 | 4-0 | Louisville | KY | |||||
| 1951-12-12 | A | 19 | Eastern Kentucky | 17 | W | 72 | 70 | 5-0 | ||||||
| 1951-12-15 | A | Purdue | 17 | L | 65 | 82 | 5-1 | |||||||
| 1951-12-18 | H | Kent State | W | 85 | 67 | 6-1 | Louisville | KY | ||||||
| 1951-12-29 | A | Manhattan | W | 67 | 66 | 7-1 | Bronx | NY | ||||||
| 1951-12-31 | A | 11 | Seton Hall | L | 65 | 67 | 7-2 | |||||||
| 1952-01-03 | H | Villanova | W | 90 | 68 | 8-2 | Louisville | KY | ||||||
| 1952-01-05 | H | 14 | Notre Dame | W | 65 | 59 | 9-2 | Louisville | KY | |||||
| 1952-01-09 | A | Xavier | 15 | W | 77 | 67 | 10-2 | |||||||
| 1952-01-12 | H | Saint Joseph's, Ind. | 15 | W | 104 | 54 | 11-2 | Louisville | KY | |||||
| 1952-01-14 | A | William & Mary | 13 | W | 93 | 65 | 12-2 | |||||||
| 1952-01-15 | A | 17 | North Carolina State | 13 | W | 73 | 68 | 13-2 | ||||||
| 1952-01-19 | H | Morehead State | 13 | W | 83 | 63 | 14-2 | Louisville | KY | |||||
| 1952-01-26 | A | Loyola-Chicago | 14 | W | 80 | 73 | 15-2 | 19,174 | Chicago | IL | Chicago Stadium | |||
| 1952-02-02 | H | Eastern Kentucky | 12 | W | 78 | 73 | 16-2 | Louisville | KY | |||||
| 1952-02-06 | H | 11 | Dayton | 13 | L | 71 | 72 | 16-3 | Louisville | KY | ||||
| 1952-02-09 | H | Tampa | 13 | W | 100 | 55 | 17-3 | Louisville | KY | |||||
| 1952-02-13 | A | Kentucky Wesleyan | 15 | W | 97 | 76 | 18-3 | |||||||
| 1952-02-16 | A | Villanova | 15 | L | 84 | 86 | 18-4 | |||||||
| 1952-02-19 | H | North Carolina State | 15 | W | 82 | 67 | 19-4 | Louisville | KY | |||||
| 1952-02-25 | H | 14 | Seton Hall | 13 | L | 81 | 83 | 19-5 | Louisville | KY | ||||
| 1952-02-27 | H | Xavier | 13 | W | 101 | 87 | 20-5 | Louisville | KY | |||||
| 1952-03-08 | N | Western Kentucky | 17 | L | 59 | 62 | 20-6 | New York | NY | Madison Square Garden III | 1952 NIT |