32 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1997-11-27 | N | Hofstra | 19 | W | 75 | 66 | 1-0 | 0-0 | 1,500 | Bayamon | PR | Eugenio Guerrero Sports Complex | 1997 Puerto Rico Shootout | |
| 1997-11-28 | N | Illinois | 19 | W | 58 | 57 | 2-0 | 0-0 | 1,500 | Bayamon | PR | Eugenio Guerrero Sports Complex | 1997 Puerto Rico Shootout | |
| 1997-11-29 | N | Georgia Tech | 19 | L | 69 | 73 | 2-1 | 0-0 | 1,500 | Bayamon | PR | Eugenio Guerrero Sports Complex | 1997 Puerto Rico Shootout | |
| 1997-12-03 | N | 3 | North Carolina | L | 72 | 81 | 2-2 | 0-0 | 19,567 | Chicago | IL | United Center | 1997 Great Eight | |
| 1997-12-06 | H | 6 | Purdue | L | 69 | 87 | 2-3 | 0-0 | 19,976 | Louisville | KY | Freedom Hall | ||
| 1997-12-09 | H | 15 | Arkansas | L | 83 | 100 | 2-4 | 0-0 | 19,523 | Louisville | KY | Freedom Hall | ||
| 1997-12-17 | H | Morehead State | W | 84 | 54 | 3-4 | 0-0 | 19,189 | Louisville | KY | Freedom Hall | |||
| 1997-12-20 | N | Georgia Tech | L | 86 | 94 | 3-5 | 0-0 | 20,793 | Atlanta | GA | Georgia Dome | 1997 Delta Airlines Classic | ||
| 1997-12-22 | H | 16 | Mississippi | L | 70 | 74 | 3-6 | 0-0 | 19,313 | Louisville | KY | Freedom Hall | ||
| 1997-12-27 | A | 4 | Kentucky | W | 79 | 76 | 4-6 | 0-0 | 24,303 | Lexington | KY | Rupp Arena | ||
| 1997-12-29 | H | Southeast Missouri State | W | 91 | 69 | 5-6 | 0-0 | 18,892 | Louisville | KY | Freedom Hall | |||
| 1998-01-03 | H | 25 | Marquette | L | 70 | 71 | 5-7 | 0-1 | 19,737 | Louisville | KY | Freedom Hall | ||
| 1998-01-06 | H | St. John's | W | 73 | 67 | 6-7 | 0-1 | 19,026 | Louisville | KY | Freedom Hall | |||
| 1998-01-08 | H | DePaul | W | 73 | 57 | 7-7 | 1-1 | 18,947 | Louisville | KY | Freedom Hall | |||
| 1998-01-10 | A | 18 | Syracuse | L | 65 | 69 | 7-8 | 1-1 | 21,197 | Syracuse | NY | Carrier Dome | ||
| 1998-01-15 | A | Alabama-Birmingham | L | 53 | 55 | 7-9 | 1-2 | 8,227 | Birmingham | AL | Bartow Arena | |||
| 1998-01-18 | H | Cincinnati | L | 57 | 71 | 7-10 | 1-3 | 19,980 | Louisville | KY | Freedom Hall | |||
| 1998-01-20 | H | Saint Louis | W | 87 | 81 | 8-10 | 2-3 | 18,705 | Louisville | KY | Freedom Hall | |||
| 1998-01-22 | A | Charlotte | L | 75 | 84 | 8-11 | 2-4 | 7,943 | Charlotte | NC | Dale F. Halton Arena | |||
| 1998-01-25 | A | 9 | UCLA | L | 82 | 88 | 8-12 | 2-4 | 10,059 | Los Angeles | CA | Pauley Pavilion | ||
| 1998-01-29 | A | 18 | Cincinnati | L | 61 | 67 | 8-13 | 2-5 | 13,176 | Cincinnati | OH | Shoemaker Center | ||
| 1998-01-31 | A | Saint Louis | L | 55 | 64 | 8-14 | 2-6 | 21,331 | St. Louis | MO | Kiel Center | |||
| 1998-02-05 | H | South Florida | L | 60 | 62 | 8-15 | 2-7 | 12,487 | Louisville | KY | Freedom Hall | |||
| 1998-02-07 | H | Tulane | W | 81 | 62 | 9-15 | 3-7 | 18,443 | Louisville | KY | Freedom Hall | |||
| 1998-02-12 | A | Houston | W | 72 | 69 | 10-15 | 4-7 | 3,011 | Houston | TX | Hofheinz Pavilion | |||
| 1998-02-15 | H | Charlotte | L | 68 | 73 | 10-16 | 4-8 | 18,893 | Louisville | KY | Freedom Hall | |||
| 1998-02-19 | A | Marquette | L | 52 | 57 | 10-17 | 4-9 | 15,743 | Milwaukee | WI | Bradley Center | |||
| 1998-02-21 | A | Memphis | L | 75 | 93 | 10-18 | 4-10 | 17,521 | Memphis | TN | The Pyramid | |||
| 1998-02-25 | H | Southern Mississippi | L | 62 | 72 | 10-19 | 4-11 | 18,224 | Louisville | KY | Freedom Hall | |||
| 1998-02-28 | A | DePaul | W | 85 | 82 | 11-19 | 5-11 | 4,927 | Chicago | IL | United Center | |||
| 1998-03-04 | N | South Florida | W | 75 | 64 | 12-19 | 5-11 | 9,282 | Cincinnati | OH | Shoemaker Center | 1998 C-USA Tournament First Round | ||
| 1998-03-05 | A | 14 | Cincinnati | L | 50 | 64 | 12-20 | 5-11 | 10,818 | Cincinnati | OH | Shoemaker Center | 1998 C-USA Tournament Quarterfinal |