Series record: 24-11 (Home: 13-3, Away: 11-5, Neutral: 0-3)
35 games
| Date | Site | Opp AP | UL AP | W/L | UL | Opp | OT | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 12/20/1947 | H | W | 64 | 42 | Louisville | Ky. | ||||||
| 01/15/2006 | H | 12 | 10 | L | 57 | 61 | 19,947 | Louisville | Ky. | Freedom Hall | ||
| 03/08/2006 | N | 8 | L | 56 | 61 | 19,594 | New York | N.Y. | Madison Square Garden IV | 2006 Big East Tournament First Round | ||
| 02/12/2007 | A | 7 | W | 66 | 53 | 12,065 | Pittsburgh | Pa. | Petersen Events Center | |||
| 03/09/2007 | N | 13 | 12 | L | 59 | 65 | 19,594 | New York | N.Y. | Madison Square Garden IV | 2007 Big East Tournament Semifinal | |
| 02/24/2008 | A | 18 | W | 75 | 73 | 12,508 | Pittsburgh | Pa. | Petersen Events Center | |||
| 03/13/2008 | N | 13 | L | 69 | 76 | OT | 19,562 | New York | N.Y. | Madison Square Garden IV | 2008 Big East Tournament Quarterfinal | |
| 01/17/2009 | H | 1 | 20 | W | 69 | 63 | 20,082 | Louisville | Ky. | Freedom Hall | ||
| 01/16/2010 | A | 16 | L | 77 | 82 | OT | 12,781 | Pittsburgh | Pa. | Petersen Events Center | ||
| 02/27/2011 | H | 4 | 16 | W | 62 | 59 | OT | 22,758 | Louisville | Ky. | KFC Yum! Center | |
| 01/21/2012 | A | 23 | W | 73 | 62 | 12,508 | Pittsburgh | Pa. | Petersen Events Center | |||
| 02/26/2012 | H | 17 | W | 57 | 54 | 22,746 | Louisville | Ky. | KFC Yum! Center | |||
| 01/28/2013 | H | 12 | W | 64 | 61 | 22,411 | Louisville | Ky. | KFC Yum! Center | |||
| 01/25/2015 | A | 10 | W | 80 | 68 | 12,508 | Pittsburgh | Pa. | Petersen Events Center | |||
| 02/11/2015 | H | 9 | W | 69 | 56 | 22,132 | Louisville | Ky. | KFC Yum! Center | |||
| 01/14/2016 | H | 20 | 21 | W | 59 | 41 | 21,632 | Louisville | Ky. | KFC Yum! Center | ||
| 02/24/2016 | A | 11 | W | 67 | 60 | 10,425 | Pittsburgh | Pa. | Petersen Events Center | |||
| 01/11/2017 | H | 14 | W | 85 | 80 | 21,558 | Louisville | Ky. | KFC Yum! Center | |||
| 01/24/2017 | A | 13 | W | 106 | 51 | 8,971 | Pittsburgh | Pa. | Petersen Events Center | |||
| 01/02/2018 | H | W | 77 | 51 | 16,461 | Louisville | Ky. | KFC Yum! Center | ||||
| 02/11/2018 | A | W | 94 | 60 | 4,772 | Pittsburgh | Pa. | Petersen Events Center | ||||
| 01/09/2019 | A | L | 86 | 89 | OT | 6,290 | Pittsburgh | Pa. | Petersen Events Center | |||
| 01/26/2019 | H | 23 | W | 66 | 51 | 16,929 | Louisville | Ky. | KFC Yum! Center | |||
| 12/06/2019 | H | 1 | W | 64 | 46 | 17,249 | Louisville | Ky. | KFC Yum! Center | |||
| 01/14/2020 | A | 11 | W | 73 | 68 | OT | 9,221 | Pittsburgh | Pa. | Petersen Events Center | ||
| 12/22/2020 | A | W | 64 | 54 | 0 | Pittsburgh | Pa. | Petersen Events Center | ||||
| 01/05/2022 | H | W | 75 | 72 | 11,973 | Louisville | Ky. | KFC Yum! Center | ||||
| 01/15/2022 | A | L | 53 | 65 | 8,431 | Pittsburgh | Pa. | Petersen Events Center | ||||
| 01/18/2023 | H | L | 54 | 75 | 11,579 | Louisville | Ky. | KFC Yum! Center | ||||
| 02/07/2023 | A | L | 57 | 91 | 7,577 | Pittsburgh | Pa. | Petersen Events Center | ||||
| 01/06/2024 | H | L | 70 | 83 | 10,883 | Louisville | Ky. | KFC Yum! Center | ||||
| 02/17/2024 | A | L | 59 | 86 | 11,419 | Pittsburgh | Pa. | Petersen Events Center | ||||
| 01/11/2025 | A | W | 82 | 78 | 9,065 | Pittsburgh | Pa. | Petersen Events Center | ||||
| 03/01/2025 | H | 19 | W | 79 | 68 | 18,459 | Louisville | Ky. | KFC Yum! Center | |||
| 01/17/2026 | A | 20 | W | 100 | 59 | 6,070 | Pittsburgh | Pa. | Petersen Events Center |