36 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2014-11-14 | N | Minnesota | 8 | W | 81 | 68 | 1-0 | 0-0 | 1,693 | Aguadilla | PR | UCSG Air Station Borinquen | 2014 Armed Forces Classic | |
| 2014-11-17 | H | Jacksonville State | 7 | W | 88 | 39 | 2-0 | 0-0 | 20,479 | Louisville | KY | KFC Yum! Center | 2014 Global Sports Showcase | |
| 2014-11-21 | H | Marshall | 7 | W | 85 | 67 | 3-0 | 0-0 | 21,661 | Louisville | KY | KFC Yum! Center | 2014 Global Sports Showcase | |
| 2014-11-24 | H | Savannah State | 6 | W | 87 | 26 | 4-0 | 0-0 | 19,514 | Louisville | KY | KFC Yum! Center | 2014 Global Sports Showcase | |
| 2014-11-26 | H | Cleveland State | 6 | W | 45 | 33 | 5-0 | 0-0 | 20,887 | Louisville | KY | KFC Yum! Center | 2014 Global Sports Showcase | |
| 2014-12-02 | H | 14 | Ohio State | 5 | W | 64 | 55 | 6-0 | 0-0 | 22,784 | Louisville | KY | KFC Yum! Center | 2014 ACC-Big Ten Challenge |
| 2014-12-05 | H | Florida International | 5 | W | 82 | 57 | 7-0 | 0-0 | 20,541 | Louisville | KY | KFC Yum! Center | ||
| 2014-12-09 | N | Indiana | 4 | W | 94 | 74 | 8-0 | 0-0 | 11,617 | New York | NY | Madison Square Garden IV | 2014 Jimmy V Classic | |
| 2014-12-14 | H | UNC Wilmington | 4 | W | 68 | 57 | 9-0 | 0-0 | 20,913 | Louisville | KY | KFC Yum! Center | 2014 Billy Minardi Classic | |
| 2014-12-20 | A | Western Kentucky | 4 | W | 76 | 67 | 10-0 | 0-0 | 7,598 | Bowling Green | KY | Diddle Arena | ||
| 2014-12-23 | H | Cal State Northridge | 4 | W | 80 | 55 | 11-0 | 0-0 | 20,231 | Louisville | KY | KFC Yum! Center | ||
| 2014-12-27 | H | 1 | Kentucky | 4 | L | 50 | 58 | 11-1 | 0-0 | 22,812 | Louisville | KY | KFC Yum! Center | 2014 Basketball Hall of Fame Shootout |
| 2014-12-30 | H | Long Beach State | 5 | W | 63 | 48 | 12-1 | 0-0 | 18,248 | Louisville | KY | KFC Yum! Center | ||
| 2015-01-04 | A | Wake Forest | 5 | W | 85 | 76 | 13-1 | 1-0 | 10,862 | Winston-Salem | NC | Lawrence Joel Veterans Memorial Coliseum | ||
| 2015-01-07 | H | Clemson | 5 | W | 58 | 52 | 14-1 | 2-0 | 21,676 | Louisville | KY | KFC Yum! Center | ||
| 2015-01-10 | A | 18 | North Carolina | 5 | L | 71 | 72 | 14-2 | 2-1 | 21,750 | Chapel Hill | NC | Dean E. Smith Center | |
| 2015-01-13 | H | Virginia Tech | 6 | W | 78 | 63 | 15-2 | 3-1 | 21,684 | Louisville | KY | KFC Yum! Center | ||
| 2015-01-17 | H | 4 | Duke | 6 | L | 52 | 63 | 15-3 | 3-2 | 22,791 | Louisville | KY | KFC Yum! Center | |
| 2015-01-25 | A | Pittsburgh | 10 | W | 80 | 68 | 16-3 | 4-2 | 12,508 | Pittsburgh | PA | Petersen Events Center | ||
| 2015-01-28 | A | Boston College | 10 | W | 81 | 72 | 17-3 | 5-2 | 5,119 | Chestnut Hill | MA | Conte Forum | ||
| 2015-01-31 | H | 13 | North Carolina | 10 | W | 78 | 68 | 18-3 | 6-2 | 22,418 | Louisville | KY | KFC Yum! Center | |
| 2015-02-03 | A | Miami, Fla. | 9 | W | 63 | 55 | 19-3 | 7-2 | 6,563 | Coral Gables | FL | BankUnited Center | ||
| 2015-02-07 | A | 3 | Virginia | 9 | L | 47 | 52 | 19-4 | 7-3 | 14,593 | Charlottesville | VA | John Paul Jones Arena | |
| 2015-02-11 | H | Pittsburgh | 9 | W | 69 | 56 | 20-4 | 8-3 | 22,132 | Louisville | KY | KFC Yum! Center | ||
| 2015-02-14 | H | North Carolina State | 9 | L | 65 | 74 | 20-5 | 8-4 | 22,410 | Louisville | KY | KFC Yum! Center | ||
| 2015-02-18 | A | Syracuse | 12 | L | 59 | 69 | 20-6 | 8-5 | 26,160 | Syracuse | NY | Carrier Dome | ||
| 2015-02-21 | H | Miami, Fla. | 12 | W | 55 | 53 | 21-6 | 9-5 | 21,345 | Louisville | KY | KFC Yum! Center | ||
| 2015-02-23 | A | Georgia Tech | 17 | W | 52 | 51 | 22-6 | 10-5 | 7,009 | Atlanta | GA | McCamish Pavilion | ||
| 2015-02-28 | A | Florida State | 17 | W | 81 | 59 | 23-6 | 11-5 | 8,844 | Tallahassee | FL | Donald L. Tucker Civic Center | ||
| 2015-03-04 | H | 12 | Notre Dame | 16 | L | 59 | 71 | 23-7 | 11-6 | 21,024 | Louisville | KY | KFC Yum! Center | |
| 2015-03-07 | H | 2 | Virginia | 16 | W | 59 | 57 | 24-7 | 12-6 | 22,788 | Louisville | KY | KFC Yum! Center | |
| 2015-03-12 | N | 19 | North Carolina | 14 | L | 60 | 70 | 24-8 | 12-6 | 22,026 | Greensboro | NC | Greensboro Coliseum | 2015 New York Life ACC Tournament Quarterfinal |
| 2015-03-20 | N | UC Irvine | 17 | W | 57 | 55 | 25-8 | 12-6 | 14,509 | Seattle | WA | KeyArena | 2015 NCAA Tournament East Regional Second Round | |
| 2015-03-22 | N | 11 | Northern Iowa | 17 | W | 66 | 53 | 26-8 | 12-6 | 14,901 | Seattle | WA | KeyArena | 2015 NCAA Tournament East Regional Third Round |
| 2015-03-27 | N | North Carolina State | 17 | W | 75 | 65 | 27-8 | 12-6 | 24,453 | Syracuse | NY | Carrier Dome | 2015 NCAA Tournament East Regional Semifinal | |
| 2015-03-29 | N | 23 | Michigan State | 17 | L | 70 | 76 | 27-9 | 12-6 | 24,404 | Syracuse | NY | Carrier Dome | 2015 NCAA Tournament East Regional Final |