32 games
| Date | Site | Opp AP | Opponent | UL AP | W/L | UL | Opp | Overall | Conf | Attendance | City | State | Arena | Event |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2002-11-23 | H | Air Force | W | 65 | 47 | 1-0 | 0-0 | 19,741 | Louisville | KY | Freedom Hall | |||
| 2002-11-30 | N | Purdue | L | 84 | 86 | 1-1 | 0-0 | 18,345 | Indianapolis | IN | Conseco Fieldhouse | 2002 John Wooden Tradition | ||
| 2002-12-07 | H | South Alabama | W | 90 | 79 | 2-1 | 0-0 | 18,987 | Louisville | KY | Freedom Hall | |||
| 2002-12-14 | A | Seton Hall | W | 91 | 70 | 3-1 | 0-0 | 7,555 | East Rutherford | NJ | Continental Airlines Arena | |||
| 2002-12-17 | H | Eastern Kentucky | W | 104 | 63 | 4-1 | 0-0 | 19,251 | Louisville | KY | Freedom Hall | 2002 Billy Minardi Classic | ||
| 2002-12-18 | H | Manhattan | W | 89 | 62 | 5-1 | 0-0 | 17,591 | Louisville | KY | Freedom Hall | 2002 Billy Minardi Classic | ||
| 2002-12-22 | H | Furman | W | 104 | 63 | 6-1 | 0-0 | 19,265 | Louisville | KY | Freedom Hall | |||
| 2002-12-28 | H | 14 | Kentucky | W | 81 | 63 | 7-1 | 0-0 | 20,061 | Louisville | KY | Freedom Hall | ||
| 2003-01-04 | A | Ohio State | 24 | W | 72 | 64 | 8-1 | 0-0 | 16,941 | Columbus | OH | Value City Arena | ||
| 2003-01-08 | A | Charlotte | 19 | W | 80 | 59 | 9-1 | 1-0 | 7,073 | Charlotte | NC | Dale F. Halton Arena | ||
| 2003-01-11 | H | Saint Louis | 19 | W | 73 | 54 | 10-1 | 2-0 | 19,486 | Louisville | KY | Freedom Hall | ||
| 2003-01-16 | A | East Carolina | 15 | W | 87 | 70 | 11-1 | 3-0 | 8,056 | Greenville | NC | Williams Arena at Minges Coliseum | ||
| 2003-01-18 | H | Texas Christian | 15 | W | 87 | 74 | 12-1 | 4-0 | 19,322 | Louisville | KY | Freedom Hall | ||
| 2003-01-22 | H | DePaul | 9 | W | 71 | 43 | 13-1 | 5-0 | 19,219 | Louisville | KY | Freedom Hall | ||
| 2003-01-25 | A | Tennessee | 9 | W | 72 | 69 | 14-1 | 5-0 | 17,084 | Knoxville | TN | Thompson-Boling Arena | ||
| 2003-01-29 | A | Southern Mississippi | 8 | W | 94 | 65 | 15-1 | 6-0 | 6,308 | Hattiesburg | MO | Reed Green Coliseum | ||
| 2003-02-01 | H | 19 | Indiana | 8 | W | 95 | 76 | 16-1 | 6-0 | 20,086 | Louisville | KY | Freedom Hall | |
| 2003-02-05 | H | Cincinnati | 5 | W | 77 | 71 | 17-1 | 7-0 | 19,942 | Louisville | KY | Freedom Hall | ||
| 2003-02-08 | A | Houston | 5 | W | 81 | 55 | 18-1 | 8-0 | 7,869 | Houston | TX | Hofheinz Pavilion | ||
| 2003-02-12 | A | Saint Louis | 2 | L | 58 | 59 | 18-2 | 8-1 | 11,338 | St. Louis | MO | Savvis Center | ||
| 2003-02-15 | A | 11 | Marquette | 2 | W | 73 | 70 | 19-2 | 9-1 | 18,850 | Milwaukee | WI | Bradley Center | |
| 2003-02-19 | H | Memphis | 4 | L | 73 | 80 | 19-3 | 9-2 | 19,786 | Louisville | KY | Freedom Hall | ||
| 2003-02-22 | A | Cincinnati | 4 | L | 80 | 101 | 19-4 | 9-3 | 13,176 | Cincinnati | OH | Shoemaker Center | ||
| 2003-02-27 | H | 10 | Marquette | 11 | L | 73 | 78 | 19-5 | 9-4 | 20,029 | Louisville | KY | Freedom Hall | |
| 2003-03-01 | H | East Carolina | 11 | W | 82 | 76 | 20-5 | 10-4 | 19,502 | Louisville | KY | Freedom Hall | ||
| 2003-03-05 | A | DePaul | 15 | L | 76 | 79 | 20-6 | 10-5 | 8,012 | Rosemont | IL | Allstate Arena | ||
| 2003-03-08 | H | Charlotte | 15 | W | 100 | 59 | 21-6 | 11-5 | 19,724 | Louisville | KY | Freedom Hall | ||
| 2003-03-13 | H | Tulane | 20 | W | 82 | 66 | 22-6 | 11-5 | 15,123 | Louisville | KY | Freedom Hall | 2003 C-USA Tournament Quarterfinal | |
| 2003-03-14 | H | 16 | Memphis | 20 | W | 78 | 75 | 23-6 | 11-5 | 18,355 | Louisville | KY | Freedom Hall | 2003 C-USA Tournament Semifinal |
| 2003-03-15 | H | Alabama-Birmingham | 20 | W | 83 | 78 | 24-6 | 11-5 | 17,202 | Louisville | KY | Freedom Hall | 2003 C-USA Tournament Final | |
| 2003-03-21 | N | Austin Peay | 14 | W | 86 | 64 | 25-6 | 11-5 | 16,467 | Birmingham | AL | BJCC Arena | 2003 NCAA Tournament East Regional First Round | |
| 2003-03-23 | N | Butler | 14 | L | 71 | 79 | 25-7 | 11-5 | 16,471 | Birmingham | AL | BJCC Arena | 2003 NCAA Tournament East Regional Second Round |